Liposomal Glutathione is a highly bioavailable antioxidant that protects cells from free radicals and aging.<\/p>\n
This product combines the best of one of the most important and highly functional antioxidants in the human body, together with Lipolife\u00ae liposomation technology.<\/p>\n
Take half a teaspoon (2.5 ml.) a day, with or without food. Can be taken directly or mixed with water or juice. Shake before use. Do not take more than 2.5 milliliters per day. <\/p>\n
Action<\/strong>: Explanation<\/strong>: Glutathione is considered the \u201cmaster\u201d antioxidant in the human body:<\/strong><\/p>\n Regenerates antioxidants vitamin C and E. GSH and oxidative stress GSH and neurodegeneration GSH and detoxification GSH and eye health GSH and fertility GSH and the immune system Glutathione and Parkinson’s disease <\/p>\n Composition<\/strong> <\/p>\n Warnings<\/strong> <\/p>\n Storage<\/strong> Liposomal Glutathione is a food supplement from Equisalud Laboratories that helps protect cells from free radicals and aging. This product comes in a glass bottle containing 100 milliliters. <\/p>\n 100 ml<\/strong><\/p>\n","protected":false},"featured_media":3451,"template":"","meta":{"_acf_changed":false,"_joinchat":[]},"product_brand":[],"product_cat":[126,89,90],"product_tag":[],"class_list":["post-3449","product","type-product","status-publish","has-post-thumbnail","product_cat-amino-acids-and-antioxidants","product_cat-food-supplements","product_cat-supplements-intrinsically-nutritious","first","outofstock","shipping-taxable","purchasable","product-type-simple"],"acf":[],"yoast_head":"\n
\nLiposomal Glutathione combines the best of one of the most important and functionally important antioxidants in the human body, together with Lipolife\u00ae liposomation technology. Glutathione has a wide range of functions, being an endogenous antioxidant that plays a key role in maintaining intracellular redox balance and detoxification of xenobiotics.
\nGlutathione shows a low absorption profile at the intestinal level, so this technology optimizes the bioavailability of its oral intake, which is otherwise inefficient. <\/p>\n
\nHighly bioavailable antioxidant that protects cells from free radicals and aging.<\/p>\n
\nRegulator of telomerase activity.
\nTransports heavy metals, e.g. Hg, out of cells and brain.
\nVital for proper mitochondrial function and for the protection and maintenance of mitochondrial DNA.
\nEssential for the detoxification and excretion of persistent organic pollutants.
\nThere is a growing recognition of the importance of glutathione (GSH) physiology and the number of physiological functions involving this small but important tripeptide. Because of its properties as an antioxidant, and its high intracellular concentration and wide distribution, its role as a potent defense mechanism against oxidative and electrophilic stress is well established.
\nHowever, as our understanding of cell signaling and regulatory pathways has developed, so has the involvement of GSH homeostasis in many other key processes, including regulation of cell proliferation and apoptosis and post-transcriptional modification of proteins through S-glutathionylation.
\nGSH is of vital importance in the detoxification of hydroperoxides and various xenobiotic compounds. In addition, GSH has been shown to be vital for mitochondrial function and mtDNA maintenance, and may be relevant to DNA methylation.
\nGiven the diverse roles of GSH in cellular physiology, the clinical significance of altered glutathione homeostasis is increasing its potential as a therapeutic agent. Alterations in GSH homeostasis have been linked to neurodegenerative disorders, liver disease, cystic fibrosis, pulmonary and cardiovascular diseases, as well as chronic age-related diseases and the aging process itself.
\nRecent data also suggest that it plays a metabolic and inflammatory role in diseases such as multiple sclerosis, metabolic syndrome and diabetes, at least in part by influencing the effect of multiple environmental toxins, an underappreciated but surprisingly significant association. <\/p>\n
\nMost GSH is utilized in antioxidant defense in cells by three members of the glutathione peroxidase (GPx) enzyme family and by one of the peroxiredoxins (Prdx 6). These enzymes catalyze the reduction of H2O2 by GSH to H2O and GSSG. Glutathione peroxidase of phospholipid hydroperoxides (PHGPx or GPx IV) can reduce lipid peroxides to lipid alcohols. GSSG is potentially toxic to cells, but high glutathione reductase activity allows most of the GSH to be maintained in reduced form. During oxidative stress GSSG could react by disulfide exchange with a protein thiol to produce a protein mixed disulfide (PSSG). In the cytosol, the formation of PSSG is transient, except during oxidative stress, and may be involved in a signal transduction mechanism in response to stress that allows its adaptation or determines its apoptosis. <\/p>\n
\nThe brain is particularly vulnerable to oxidative stress due to relatively lower antioxidant enzyme activities (SOD, GPx, GR and catalase) compared to other tissues. The brain requires a large amount of O2, leading to high production of oxygen radicals (ROS) and subsequent lipid peroxidation.
\nIn addition to decreasing oxidative stress in the brain, glutathione improves mental clarity and memory, as well as helps prevent the formation of amyloid plaques.Intracellular GSH levels are inversely related to cell viability under oxidative stress in cultured neurons. <\/p>\n
\nGlutathione is the main defense for removing chemicals and toxins from our bodies.
\nThe removal of many xenobiotic compounds can be achieved by conjugation with GSH followed by its secretion from the cell. This reaction occurs mostly by an enzymatically catalyzed addition by a glutathione-S transferase (GST). The glutathione adduct can be secreted from cells via a membrane transporter. <\/p>\n
\nThe GSH content in the eye is high due to its protective action against harmful UV rays. Other benefits of its presence in the eye include the possible prevention of cataract development. <\/p>\n
\nAt conception, sperm and egg fuse in a process dependent on the presence of glutathione. Research has indicated that increasing glutathione levels may improve fertility, especially in men. <\/p>\n
\nIn addition to its function as an intracellular redox buffer, GSH plays a key role in the immune system and in the antiviral and inflammatory response. Regarding the inflammatory response, it has been shown that intracellular GSH depletion represents the first event in the signaling process. This alteration is accompanied by an increase in the production of cytokines, such as tumor necrosis factor (TNF-\u03b1), and the interleukins IL-1\u03b2, IL-6 and IL-8. Changes in intracellular GSH levels also characterize the polarization of M1 and M2 macrophages.
\nIt has been shown that a low GSH\/GSSG ratio determines a decrease in IL-12 production and ultimately a shift from Th1 to Th2 response. Conversely, high GSH\/GSSG ratio in macrophages restores high IL-12 production favoring Th1 response patterns.
\nGSH depletion also represents a key factor in the activation of cell-autonomous inflammation, such as in aged adipose and skeletal muscle tissues. Therefore, alteration of the GSH\/GSSG ratio appears to be a common factor in the regulation of macrophage and cell-autonomous cellular inflammation. <\/p>\n
\nSeveral studies have demonstrated a deficiency in reduced glutathione (GSH) in the substantia nigra of patients with Parkinson’s disease (PD). Notably, the magnitude of GSH depletion appears to parallel disease severity. This finding may indicate a means by which substantia nigra cells could be therapeutically supported. The authors of a study investigated the effects of GSH in nine patients with untreated early PD. GSH was administered intravenously, 600 mg twice daily, for 30 days, in an open-label fashion. GSH was then discontinued and a follow-up examination was performed at 1-month intervals for 2 to 4 months. Subsequently, patients were treated with carbidopa-levodopa. Clinical disability was assessed at baseline and at 1-month interval for 4 to 6 months by using two different rating scales and the Webster Step-Second Test. All patients improved significantly after GSH therapy, with a 42% decrease in disability. Once GSH was stopped, the therapeutic effect lasted 2 to 4 months. The authors concluded: \u201cthe data indicate that, in untreated PD patients, GSH has symptomatic efficacy and possibly delays disease progression\u201d. <\/p>\n
\nPer 2.5 ml:
\nReduced glutathione, 225 mg; vitamin E (D-alpha-tocopherol).<\/p>\n
\nFood supplement based on glutathione. Food supplements should not be used as substitutes for a varied and balanced diet. Do not exceed the expressly recommended daily dose. Keep out of reach of young children.<\/p>\n
\nKeep container tightly closed, dry and cool.<\/p>\n","protected":false},"excerpt":{"rendered":"